Saturday, June 26, 2010

ribosomes 399 Louis J. Sheehan, Esquire

The system doesn’t allow me to attach the slides. Instead, I have numbered the slides and then listed the relevant slides.





1. Structure of ribosomes


More than 50 different proteins and several ribonucleic molecules are combined to comprise ribosomes. Ribosomes are composed of 1/3 protein and 2/3 RNA. RNA forms the core of the ribosome and proteins are found on the ribosomal surface. In eukaryotes, ribosomal subunits are constructed in the nucleus and are then exported to the cytoplasm where, when joined together, they catalyze the construction of and construct protein.

Prokaryotic and eukaryotic ribosomes are similar. In each case, they have (i) a small subunit and (ii) a large subunit. The two subunits are linked together on an mRNA molecule – typically near its 5’ end – when it is appropriate to initiate the synthesis of proteins. The small subunit is where the matching of the tRNAs and the codons of the mRNA takes place. The large subunit is where the polypeptide chain is constructed by bonding amino acids together. To translate the mRNA, the ribosome pulls the mRNA through its core.

Sunday, June 6, 2010

Dublin 449.dub.002 Louis J. Sheehan, Esquire

Ireland is known as a land of legends, poetry, beauty and resolute spirit. Ireland is also known to many as the home of Sr. Margaret MacCurtain, a remarkable woman with a most determined spirit. To many in her homeland and throughout the world, she is known as a champion of justice for all, especially for women and children.

Sr. MacCurtain recently retired as a Lecturer from the Irish History Department of University College Dublin, 1964-94. During those years she was also Professor at the School of Irish Studies, Dublin, 1972-89. A member of the Academic Council of the Irish School of Ecumenics, for many years she served on the Catholic Communications Council set up by the Catholic hierarchy after Vatican Two. She was a board member of the National Rehabilitation Institute and as the founder principal helped establish the Senior College Ballyfermont for public education in the city of Dublin. A Dominican Sister, she was the prioress of Sion Hill convent and currently chairs the Board of Governors of St. Catherine's Home Economics College in Sion Hill. She held the Burns Chair of Irish Studies in Boston College, 1992-93, and more recently was the Baldwin Scholar in the College of Notre Dame of Maryland (Baltimore). Her research into the history of Irish women won her the award of the Eire Society of Boston Gold Medal in 1993. Sr. MacCurtain is an internationally recognized and honored scholar, educator, writer, innovator, and feminist activist; put it all together and she is the complete Humanist.